Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity

[Image: see text] Recent studies have shown that nuclear transcription factor cyclic adenosine monophosphate response element binding protein (CREB) is overexpressed in many different types of cancers. Therefore, CREB has been pursued as a novel cancer therapeutic target. Naphthol AS-E and its close...

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Detalles Bibliográficos
Autores principales: Xie, Fuchun, Li, Bingbing X., Kassenbrock, Alina, Xue, Changhui, Wang, Xiaoyan, Qian, David Z., Sears, Rosalie C., Xiao, Xiangshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493896/
https://www.ncbi.nlm.nih.gov/pubmed/26023867
http://dx.doi.org/10.1021/acs.jmedchem.5b00468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493896/
https://www.ncbi.nlm.nih.gov/pubmed/26023867
http://dx.doi.org/10.1021/acs.jmedchem.5b00468

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