Validation and selection of ODE based systems biology models: how to arrive at more reliable decisions

BACKGROUND: Most ordinary differential equation (ODE) based modeling studies in systems biology involve a hold-out validation step for model validation. In this framework a pre-determined part of the data is used as validation data and, therefore it is not used for estimating the parameters of the m...

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Detalles Bibliográficos
Autores principales: Hasdemir, Dicle, Hoefsloot, Huub C.J, Smilde, Age K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493957/
https://www.ncbi.nlm.nih.gov/pubmed/26152206
http://dx.doi.org/10.1186/s12918-015-0180-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493957/
https://www.ncbi.nlm.nih.gov/pubmed/26152206
http://dx.doi.org/10.1186/s12918-015-0180-0

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