VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity

Cytotoxic T lymphocytes (CTLs) eliminate infected and neoplastic cells through directed release of cytotoxic granule contents. Although multiple SNARE proteins have been implicated in cytotoxic granule exocytosis, the role of vesicular SNARE proteins, i.e., vesicle-associated membrane proteins (VAMP...

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Detalles Bibliográficos
Autores principales: Marshall, Misty R., Pattu, Varsha, Halimani, Mahantappa, Maier-Peuschel, Monika, Müller, Martha-Lena, Becherer, Ute, Hong, Wanjin, Hoth, Markus, Tschernig, Thomas, Bryceson, Yenan T., Rettig, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493996/
https://www.ncbi.nlm.nih.gov/pubmed/26124288
http://dx.doi.org/10.1083/jcb.201411093