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VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity
Cytotoxic T lymphocytes (CTLs) eliminate infected and neoplastic cells through directed release of cytotoxic granule contents. Although multiple SNARE proteins have been implicated in cytotoxic granule exocytosis, the role of vesicular SNARE proteins, i.e., vesicle-associated membrane proteins (VAMP...
Autores principales: | Marshall, Misty R., Pattu, Varsha, Halimani, Mahantappa, Maier-Peuschel, Monika, Müller, Martha-Lena, Becherer, Ute, Hong, Wanjin, Hoth, Markus, Tschernig, Thomas, Bryceson, Yenan T., Rettig, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493996/ https://www.ncbi.nlm.nih.gov/pubmed/26124288 http://dx.doi.org/10.1083/jcb.201411093 |
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