Transposable Elements and DNA Methylation Create in Embryonic Stem Cells Human-Specific Regulatory Sequences Associated with Distal Enhancers and Noncoding RNAs

Despite significant progress in the structural and functional characterization of the human genome, understanding of the mechanisms underlying the genetic basis of human phenotypic uniqueness remains limited. Here, I report that transposable element-derived sequences, most notably LTR7/HERV-H, LTR5_...

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Detalles Bibliográficos
Autor principal: Glinsky, Gennadi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494056/
https://www.ncbi.nlm.nih.gov/pubmed/25956794
http://dx.doi.org/10.1093/gbe/evv081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494056/
https://www.ncbi.nlm.nih.gov/pubmed/25956794
http://dx.doi.org/10.1093/gbe/evv081

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