Polymorphism Analysis Reveals Reduced Negative Selection and Elevated Rate of Insertions and Deletions in Intrinsically Disordered Protein Regions

Intrinsically disordered protein regions are abundant in eukaryotic proteins and lack stable tertiary structures and enzymatic functions. Previous studies of disordered region evolution based on interspecific alignments have revealed an increased propensity for indels and rapid rates of amino acid s...

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Detalles Bibliográficos
Autores principales: Khan, Tahsin, Douglas, Gavin M., Patel, Priyenbhai, Nguyen Ba, Alex N., Moses, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494057/
https://www.ncbi.nlm.nih.gov/pubmed/26047845
http://dx.doi.org/10.1093/gbe/evv105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494057/
https://www.ncbi.nlm.nih.gov/pubmed/26047845
http://dx.doi.org/10.1093/gbe/evv105

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