What Does It Take to Evolve an Enhancer? A Simulation-Based Study of Factors Influencing the Emergence of Combinatorial Regulation

There is widespread interest today in understanding enhancers, which are regulatory elements typically harboring several transcription factor binding sites and mediating the combinatorial effect of transcription factors on gene expression. The evolution of enhancers poses interesting unanswered ques...

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Detalles Bibliográficos
Autores principales: Duque, Thyago, Sinha, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494070/
https://www.ncbi.nlm.nih.gov/pubmed/25956793
http://dx.doi.org/10.1093/gbe/evv080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494070/
https://www.ncbi.nlm.nih.gov/pubmed/25956793
http://dx.doi.org/10.1093/gbe/evv080

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