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RAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function?
The protein complex including Mre11, Rad50, and Nbs1 (MRN) functions in DNA double-strand break repair to recognize and process DNA ends as well as signal for cell cycle arrest. Amino acid sequence similarity and overall architecture make Rad50 a member of the structural maintenance of chromosome (S...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494100/ https://www.ncbi.nlm.nih.gov/pubmed/19308707 http://dx.doi.org/10.1007/s10577-008-9018-6 |