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RAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function?

The protein complex including Mre11, Rad50, and Nbs1 (MRN) functions in DNA double-strand break repair to recognize and process DNA ends as well as signal for cell cycle arrest. Amino acid sequence similarity and overall architecture make Rad50 a member of the structural maintenance of chromosome (S...

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Detalles Bibliográficos
Autores principales: Kinoshita, Eri, van der Linden, Eddy, Sanchez, Humberto, Wyman, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494100/
https://www.ncbi.nlm.nih.gov/pubmed/19308707
http://dx.doi.org/10.1007/s10577-008-9018-6