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Native Liquid Extraction Surface Analysis Mass Spectrometry: Analysis of Noncovalent Protein Complexes Directly from Dried Substrates

Liquid extraction surface analysis (LESA) mass spectrometry is a promising tool for the analysis of intact proteins from biological substrates. Here, we demonstrate native LESA mass spectrometry of noncovalent protein complexes of myoglobin and hemoglobin from a range of surfaces. Holomyoglobin, in...

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Detalles Bibliográficos
Autores principales: Martin, Nicholas J., Griffiths, Rian L., Edwards, Rebecca L., Cooper, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494149/
https://www.ncbi.nlm.nih.gov/pubmed/25990922
http://dx.doi.org/10.1007/s13361-015-1152-8