Nonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes

The use of vincristine (VCR) to treat cancer has been limited by its dose-dependent toxicity and development of drug resistance after repeated administrations. In this study, we investigated the mechanism by which quinine hydrochloride (QN) acts as a sensitizer for VCR. Our experiments used three ki...

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Detalles Bibliográficos
Autores principales: Xu, Yuzhen, Qiu, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494179/
https://www.ncbi.nlm.nih.gov/pubmed/26170660
http://dx.doi.org/10.2147/IJN.S84555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494179/
https://www.ncbi.nlm.nih.gov/pubmed/26170660
http://dx.doi.org/10.2147/IJN.S84555

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