Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males

Lesinurad is a selective uric acid reabsorption inhibitor under investigation for the treatment of gout. Single and multiple ascending dose studies were conducted to evaluate pharmacokinetics, pharmacodynamics, and safety of lesinurad in healthy males. Lesinurad was administered as an oral solution...

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Detalles Bibliográficos
Autores principales: Shen, Zancong, Rowlings, Colin, Kerr, Brad, Hingorani, Vijay, Manhard, Kimberly, Quart, Barry, Yeh, Li-Tain, Storgard, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494180/
https://www.ncbi.nlm.nih.gov/pubmed/26170627
http://dx.doi.org/10.2147/DDDT.S85193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494180/
https://www.ncbi.nlm.nih.gov/pubmed/26170627
http://dx.doi.org/10.2147/DDDT.S85193

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