Gene Expression Driven by a Strong Viral Promoter in MVA Increases Vaccination Efficiency by Enhancing Antibody Responses and Unmasking CD8(+) T Cell Epitope

Viral vectors are promising tools for vaccination strategies and immunotherapies. However, CD8(+) T cell responses against pathogen-derived epitopes are usually limited to dominant epitopes and antibody responses to recombinant encoded antigens (Ags) are mostly weak. We have previously demonstrated...

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Detalles Bibliográficos
Autores principales: Becker, Pablo D., Nörder, Miriam, Weissmann, Sebastian, Ljapoci, Ronny, Erfle, Volker, Drexler, Ingo, Guzmán, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494220/
https://www.ncbi.nlm.nih.gov/pubmed/26344747
http://dx.doi.org/10.3390/vaccines2030581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494220/
https://www.ncbi.nlm.nih.gov/pubmed/26344747
http://dx.doi.org/10.3390/vaccines2030581

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