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Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation

The skin is an attractive tissue for vaccination in a clinical setting due to the accessibility of the target, the ease of monitoring and most importantly the immune competent nature of the dermal tissue. While skin electroporation offers an exciting and novel future methodology for the delivery of...

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Detalles Bibliográficos
Autores principales: Mendoza, Janess M., Amante, Dinah H., Kichaev, Gleb, Knott, Christine L., Kiosses, William B., Smith, Trevor R. F., Sardesai, Niranjan Y., Broderick, Kate E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494224/
https://www.ncbi.nlm.nih.gov/pubmed/26344120
http://dx.doi.org/10.3390/vaccines1030384