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Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

Nucleic acid-based vaccines such as viral vectors, plasmid DNA (pDNA), and mRNA are being developed as a means to address limitations of both live-attenuated and subunit vaccines. DNA vaccines have been shown to be potent in a wide variety of animal species and several products are now licensed for...

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Detalles Bibliográficos
Autores principales: Cu, Yen, Broderick, Kate E., Banerjee, Kaustuv, Hickman, Julie, Otten, Gillis, Barnett, Susan, Kichaev, Gleb, Sardesai, Niranjan Y., Ulmer, Jeffrey B., Geall, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494232/
https://www.ncbi.nlm.nih.gov/pubmed/26344119
http://dx.doi.org/10.3390/vaccines1030367