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Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ
Nucleic acid-based vaccines such as viral vectors, plasmid DNA (pDNA), and mRNA are being developed as a means to address limitations of both live-attenuated and subunit vaccines. DNA vaccines have been shown to be potent in a wide variety of animal species and several products are now licensed for...
Autores principales: | Cu, Yen, Broderick, Kate E., Banerjee, Kaustuv, Hickman, Julie, Otten, Gillis, Barnett, Susan, Kichaev, Gleb, Sardesai, Niranjan Y., Ulmer, Jeffrey B., Geall, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494232/ https://www.ncbi.nlm.nih.gov/pubmed/26344119 http://dx.doi.org/10.3390/vaccines1030367 |
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