Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques

HIV-1 DNA vaccines have many advantageous features. Evaluation of HIV-1 vaccine candidates often starts in small animal models before macaque and human trials. Here, we selected and optimized DNA vaccine candidates through systematic testing in rabbits for the induction of broadly neutralizing antib...

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Detalles Bibliográficos
Autores principales: Borggren, Marie, Vinner, Lasse, Andresen, Betina Skovgaard, Grevstad, Berit, Repits, Johanna, Melchers, Mark, Elvang, Tara Laura, Sanders, Rogier W, Martinon, Frédéric, Dereuddre-Bosquet, Nathalie, Bowles, Emma Joanne, Stewart-Jones, Guillaume, Biswas, Priscilla, Scarlatti, Gabriella, Jansson, Marianne, Heyndrickx, Leo, Le Grand, Roger, Fomsgaard, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494233/
https://www.ncbi.nlm.nih.gov/pubmed/26344115
http://dx.doi.org/10.3390/vaccines1030305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494233/
https://www.ncbi.nlm.nih.gov/pubmed/26344115
http://dx.doi.org/10.3390/vaccines1030305

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