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Epitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte Epitopes

Tumor vaccine design requires prediction and validation of immunogenic MHC class I epitopes expressed by target cells as well as MHC class II epitopes expressed by antigen-presenting cells essential for the induction of optimal immune responses. Epitope prediction methods are based on different algo...

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Detalles Bibliográficos
Autores principales: Ip, Peng Peng, Nijman, Hans W., Daemen, Toos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494349/
https://www.ncbi.nlm.nih.gov/pubmed/26343185
http://dx.doi.org/10.3390/vaccines3020203