Integrating Immune Checkpoint Blockade with Anti-Neo/Mutated Antigens Reactivity to Increase the Clinical Outcome of Immunotherapy

Antibodies to immune checkpoints have entered the clinical arena and have been shown to provide a clinical benefit for metastatic melanoma and, possibly, for other tumors as well. In this review paper we summarize this therapeutic activity and underline the functional mechanisms that may be involved...

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Detalles Bibliográficos
Autores principales: Parmiani, Giorgio, Maccalli, Cristina, Maio, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494352/
https://www.ncbi.nlm.nih.gov/pubmed/26343195
http://dx.doi.org/10.3390/vaccines3020420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494352/
https://www.ncbi.nlm.nih.gov/pubmed/26343195
http://dx.doi.org/10.3390/vaccines3020420

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