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The MAPK signaling pathway mediates the GPR91-dependent release of VEGF from RGC-5 cells

Vascular endothelial growth factor (VEGF) is one of the major regulatory molecules in diabetic retinopathy (DR). In our previous study, we demonstrated that succinate levels were elevated in the retinas of diabetic rats and that the knockdown of the succinate receptor, G-protein-coupled receptor 91...

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Detalles Bibliográficos
Autores principales: HU, JIANYAN, LI, TINGTING, DU, SHANSHAN, CHEN, YONGDONG, WANG, SHUAI, XIONG, FEN, WU, QIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494573/
https://www.ncbi.nlm.nih.gov/pubmed/25936351
http://dx.doi.org/10.3892/ijmm.2015.2195