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Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells

Epithelial-mesenchymal transition (EMT), a process closely related to tumor development, is regulated by a variety of signaling pathways and growth factors, such as transforming growth factor-β1 (TGF-β1) and epidermal growth factor (EGF). Hyaluronan (HA) has been shown to induce EMT through either T...

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Detalles Bibliográficos
Autores principales: LI, LINGMEI, QI, LISHA, LIANG, ZHIJIE, SONG, WANGZHAO, LIU, YANXUE, WANG, YALEI, SUN, BAOCUN, ZHANG, BIN, CAO, WENFENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494581/
https://www.ncbi.nlm.nih.gov/pubmed/26005723
http://dx.doi.org/10.3892/ijmm.2015.2222