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Combination treatment with ethyl pyruvate and IGF-I exerts neuroprotective effects against brain injury in a rat model of neonatal hypoxic-ischemic encephalopathy

Neonatal hypoxic-ischemic (HI) brain injury causes severe brain damage in newborns. Following HI injury, rapidly accumulating oxidants injure neurons and interrupt ongoing developmental processes. The antioxidant, sodium pyruvate, has been shown to reduce neuronal injury in neonatal rats under condi...

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Detalles Bibliográficos
Autores principales: RONG, ZHIHUI, PAN, RUI, CHANG, LIWEN, LEE, WEIHUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494588/
https://www.ncbi.nlm.nih.gov/pubmed/25999282
http://dx.doi.org/10.3892/ijmm.2015.2219