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Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer

Metformin, a widely prescribed antidiabetic drug, has previously been shown to lower the risk of certain types of cancer, including that of breast cancer, and to improve prognosis. Its anticancer effects, which are mediated by the activation of AMP-activated protein kinase (AMPK), have become notabl...

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Detalles Bibliográficos
Autores principales: FAN, CONG, WANG, YUNSHAN, LIU, ZIMING, SUN, YING, WANG, XIUWEN, WEI, GUANGWEI, WEI, JUNMIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494591/
https://www.ncbi.nlm.nih.gov/pubmed/25999130
http://dx.doi.org/10.3892/ijmm.2015.2217