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Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer
Metformin, a widely prescribed antidiabetic drug, has previously been shown to lower the risk of certain types of cancer, including that of breast cancer, and to improve prognosis. Its anticancer effects, which are mediated by the activation of AMP-activated protein kinase (AMPK), have become notabl...
Autores principales: | FAN, CONG, WANG, YUNSHAN, LIU, ZIMING, SUN, YING, WANG, XIUWEN, WEI, GUANGWEI, WEI, JUNMIN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494591/ https://www.ncbi.nlm.nih.gov/pubmed/25999130 http://dx.doi.org/10.3892/ijmm.2015.2217 |
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