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Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets

The number of pro-α cells is known to increase in response to β cell injury and these cells then generate glucagon-like peptide-1 (GLP-1), thus attenuating the development of diabetes. The aim of the present study was to further examine the role and the mechanisms responsible for intra-islet GLP-1 p...

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Detalles Bibliográficos
Autores principales: HUANG, CHENGHU, YUAN, LI, CAO, SHUYI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494597/
https://www.ncbi.nlm.nih.gov/pubmed/25976560
http://dx.doi.org/10.3892/ijmm.2015.2207