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Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets
The number of pro-α cells is known to increase in response to β cell injury and these cells then generate glucagon-like peptide-1 (GLP-1), thus attenuating the development of diabetes. The aim of the present study was to further examine the role and the mechanisms responsible for intra-islet GLP-1 p...
Autores principales: | HUANG, CHENGHU, YUAN, LI, CAO, SHUYI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494597/ https://www.ncbi.nlm.nih.gov/pubmed/25976560 http://dx.doi.org/10.3892/ijmm.2015.2207 |
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