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CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis

Epidural fibrosis is characterized by the development of dense and thick scar tissue adjacent to the dural mater and ranked as the major contributor for post-operative pain recurrence after laminectomy or discectomy. Recently, CCN5 exhibited an inhibitory effect on connective tissue growth factor (C...

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Detalles Bibliográficos
Autores principales: XU, HONGHAI, LIU, CONG, SUN, ZHENGMING, GUO, XIONG, ZHANG, YUELIN, LIU, MENGTING, LI, PENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494601/
https://www.ncbi.nlm.nih.gov/pubmed/25901787
http://dx.doi.org/10.3892/ijmm.2015.2190