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CaCO(3)/CaIP(6) composite nanoparticles effectively deliver AKT1 small interfering RNA to inhibit human breast cancer growth

BACKGROUND: Small interfering RNA (siRNA)-mediated gene therapy is a promising strategy to temporarily inhibit the expression of genes involved in development of breast cancer. The lack of a safe and efficient gene delivery system has become a major hurdle for siRNA-mediated gene therapy in breast c...

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Detalles Bibliográficos
Autores principales: Zhou, Hongyan, Wei, Jinhuan, Dai, Qiangsheng, Wang, Liping, Luo, Junhang, Cheang, Tuckyun, Wang, Shenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494612/
https://www.ncbi.nlm.nih.gov/pubmed/26170662
http://dx.doi.org/10.2147/IJN.S73269