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CaCO(3)/CaIP(6) composite nanoparticles effectively deliver AKT1 small interfering RNA to inhibit human breast cancer growth
BACKGROUND: Small interfering RNA (siRNA)-mediated gene therapy is a promising strategy to temporarily inhibit the expression of genes involved in development of breast cancer. The lack of a safe and efficient gene delivery system has become a major hurdle for siRNA-mediated gene therapy in breast c...
Autores principales: | Zhou, Hongyan, Wei, Jinhuan, Dai, Qiangsheng, Wang, Liping, Luo, Junhang, Cheang, Tuckyun, Wang, Shenming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494612/ https://www.ncbi.nlm.nih.gov/pubmed/26170662 http://dx.doi.org/10.2147/IJN.S73269 |
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