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T1-Weighted Hypersignal in the Deep Cerebellar Nuclei After Repeated Administrations of Gadolinium-Based Contrast Agents in Healthy Rats: Difference Between Linear and Macrocyclic Agents

OBJECTIVES: To prospectively compare in healthy rats the effect of multiple injections of macrocyclic (gadoterate meglumine) and linear (gadodiamide) gadolinium-based contrast agents (GBCAs) on T1-weighted signal intensity in the deep cerebellar nuclei (DCN), including the dentate nucleus. MATERIALS...

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Detalles Bibliográficos
Autores principales: Robert, Philippe, Lehericy, Stéphane, Grand, Sylvie, Violas, Xavier, Fretellier, Nathalie, Idée, Jean-Marc, Ballet, Sébastien, Corot, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494686/
https://www.ncbi.nlm.nih.gov/pubmed/26107651
http://dx.doi.org/10.1097/RLI.0000000000000181