Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy

Glioblastoma (GBM) is the most common and deadly primary brain tumor in adults. Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor (VEGF), can attenuate tumor-associated edema and improve patient symptoms but based on magnetic resonance imaging, is associated wit...

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Detalles Bibliográficos
Autores principales: Xu, Hui, Rahimpour, Shervin, Nesvick, Cody L., Zhang, Xu, Ma, Jingyun, Zhang, Min, Zhang, Ge, Wang, Li, Yang, Chunzhang, Hong, Christopher S., Germanwala, Anand V., Elder, J. Bradley, Ray-Chaudhury, Abhik, Yao, Yu, Gilbert, Mark R., Lonser, Russell R., Heiss, John D., Brady, Roscoe O., Mao, Ying, Qin, Jianhua, Zhuang, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494911/
https://www.ncbi.nlm.nih.gov/pubmed/25957416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494911/
https://www.ncbi.nlm.nih.gov/pubmed/25957416

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