Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer

Non-small cell lung cancer (NSCLC) remains the most common cause of cancer death worldwide due its resistance to chemotherapy and aggressive tumor growth. Polo-like kinase 1 (PLK1) is a serine-threonine protein kinase which is overexpressed in cancer cells, and plays a major role in regulating tumor...

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Detalles Bibliográficos
Autores principales: McCarroll, Joshua A., Dwarte, Tanya, Baigude, Huricha, Dang, Jason, Yang, Lu, Erlich, Rafael B., Kimpton, Kathleen, Teo, Joann, Sagnella, Sharon M., Akerfeldt, Mia C., Liu, Jie, Phillips, Phoebe A., Rana, Tariq M., Kavallaris, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494920/
https://www.ncbi.nlm.nih.gov/pubmed/25557168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494920/
https://www.ncbi.nlm.nih.gov/pubmed/25557168

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