Combining TGF-β1 knockdown and miR200c administration to optimize antitumor efficacy of B16F10/GPI-IL-21 vaccine

TGF-β1 secreted abundantly by tumors cells as well as present in the local microenvironment promotes neoplasm invasion and metastasis by triggering the epithelial to mesenchymal transition (EMT). MiR200c has been shown to suppress EMT and to regulate the cellular epithelial and interstitial state co...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoying, Zhao, Fengshu, He, Xiangfeng, Wang, Jing, Zhang, Ying, Zhang, Hongyi, Ni, Yaoyao, Sun, Jianan, Wang, Xiaobing, Dou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494953/
https://www.ncbi.nlm.nih.gov/pubmed/25895132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494953/
https://www.ncbi.nlm.nih.gov/pubmed/25895132

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