A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations

Here we studied the relevance and modulation of aldehyde dehydrogenase (ALDH) expression in malignant pleural mesothelioma (MPM) chemoresistant cell subpopulations (ALDH(bright) cells), which survive pemetrexed + cisplatin treatment in vitro and in vivo. Expression of the ALDH1A3 isoform was invaria...

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Detalles Bibliográficos
Autores principales: Canino, Claudia, Luo, YuYing, Marcato, Paola, Blandino, Giovanni, Pass, Harvey I., Cioce, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494963/
https://www.ncbi.nlm.nih.gov/pubmed/25868979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494963/
https://www.ncbi.nlm.nih.gov/pubmed/25868979

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