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Kinetics of lung tissue factor expression and procoagulant activity in bleomycin induced acute lung injury

BACKGROUND: Activation of coagulation by expression of tissue factor (TF) in the airspace is a hallmark of acute lung injury (ALI) but the timing of TF activation in relationship to increases in lung permeability and inflammation are unknown. METHODS: To test the hypothesis that TF is upregulated ea...

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Detalles Bibliográficos
Autores principales: Ma, Li, Shaver, Ciara M., Grove, Brandon S., Mitchell, Daphne B., Wickersham, Nancy E., Carnahan, Robert H., Cooper, Tracy L., Brake, Brittany E., Ware, Lorraine B., Bastarache, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495096/
https://www.ncbi.nlm.nih.gov/pubmed/26154059
http://dx.doi.org/10.1186/s40169-015-0063-4