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Addressing the link between paraoxonase-1 gene variants and the incidence of early onset myocardial infarction

INTRODUCTION: The enzyme paraoxonase-1 (PON1) represents an endogenous defense mechanism against vascular oxidative stress, thereby contributing to the prevention of atherosclerosis. Several polymorphisms have been reported in the PON1 gene, including Q192R. PON1 phenotype is commonly expressed as t...

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Detalles Bibliográficos
Autores principales: Rahman, Mohamed F. Abdel, Hashad, Ingy M., Abou-Aisha, Khaled, Abdel-Maksoud, Sahar M., Gad, Mohamed Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495147/
https://www.ncbi.nlm.nih.gov/pubmed/26170843
http://dx.doi.org/10.5114/aoms.2015.52353