The somatic autosomal mutation matrix in cancer genomes

DNA damage in somatic cells originates from both environmental and endogenous sources, giving rise to mutations through multiple mechanisms. When these mutations affect the function of critical genes, cancer may ensue. Although identifying genomic subsets of mutated genes may inform therapeutic opti...

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Detalles Bibliográficos
Autores principales: Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Vasquez, Karen M., Cooper, David N., Mudunuri, Uma, Ivanic, Joseph, Cer, Regina Z., Yi, Ming, Stephens, Robert M., Collins, Jack R., Luke, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495249/
https://www.ncbi.nlm.nih.gov/pubmed/26001532
http://dx.doi.org/10.1007/s00439-015-1566-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495249/
https://www.ncbi.nlm.nih.gov/pubmed/26001532
http://dx.doi.org/10.1007/s00439-015-1566-1

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