Cargando…

The somatic autosomal mutation matrix in cancer genomes

DNA damage in somatic cells originates from both environmental and endogenous sources, giving rise to mutations through multiple mechanisms. When these mutations affect the function of critical genes, cancer may ensue. Although identifying genomic subsets of mutated genes may inform therapeutic opti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Temiz, Nuri A., Donohue, Duncan E., Bacolla, Albino, Vasquez, Karen M., Cooper, David N., Mudunuri, Uma, Ivanic, Joseph, Cer, Regina Z., Yi, Ming, Stephens, Robert M., Collins, Jack R., Luke, Brian T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495249/ https://www.ncbi.nlm.nih.gov/pubmed/26001532 http://dx.doi.org/10.1007/s00439-015-1566-1

Ejemplares similares

Erratum to: The somatic autosomal mutation matrix in cancer genomes
por: Temiz, Nuri A., et al.
Publicado: (2015)

Guanine Holes Are Prominent Targets for Mutation in Cancer and Inherited Disease
por: Bacolla, Albino, et al.
Publicado: (2013)

Introducing the non-B DNA Motif Search Tool (nBMST)
por: Cer, Regina Z, et al.
Publicado: (2011)

Non-B DB v2.0: a database of predicted non-B DNA-forming motifs and its associated tools
por: Cer, Regina Z., et al.
Publicado: (2013)

The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA
por: Temiz, Nuri A., et al.
Publicado: (2012)

Non-B DB: a database of predicted non-B DNA-forming motifs in mammalian genomes
por: Cer, Regina Z., et al.
Publicado: (2011)

The Zinc-Dependent Protease Activity of the Botulinum Neurotoxins
por: Lebeda, Frank J., et al.
Publicado: (2010)

Mechanisms of Base Substitution Mutagenesis in Cancer Genomes
por: Bacolla, Albino, et al.
Publicado: (2014)

DNA structure matters
por: Bacolla, Albino, et al.
Publicado: (2013)

Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences
por: Bacolla, Albino, et al.
Publicado: (2016)

New Perspectives on DNA and RNA Triplexes As Effectors of Biological Activity
por: Bacolla, Albino, et al.
Publicado: (2015)

IC(50)-to-K(i): a web-based tool for converting IC(50) to K(i) values for inhibitors of enzyme activity and ligand binding
por: Cer, R. Z., et al.
Publicado: (2009)

Local DNA dynamics shape mutational patterns of mononucleotide repeats in human genomes
por: Bacolla, Albino, et al.
Publicado: (2015)

Choroideremia associated with an X-autosomal translocation
por: Siu, Victoria M., et al.
Publicado: (1990)

Strategies for Outcrossing and Genetic Manipulation of Drosophila Compound Autosome Stocks
por: Martins, Torcato, et al.
Publicado: (2013)

Autosomal Admixture Levels Are Informative About Sex Bias in Admixed Populations
por: Goldberg, Amy, et al.
Publicado: (2014)

RNA sequencing-based screen for reactivation of silenced alleles of autosomal genes
por: Gupta, Saumya, et al.
Publicado: (2021)

Seeking unique and common biological themes in multiple gene lists or datasets: pathway pattern extraction pipeline for pathway-level comparative analysis
por: Yi, Ming, et al.
Publicado: (2009)

A Genome-Wide Screen Identifies Genes That Affect Somatic Homolog Pairing in Drosophila
por: Bateman, Jack R., et al.
Publicado: (2012)

DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells
por: Jain, Aklank, et al.
Publicado: (2013)

A Simplified Strategy for Introducing Genetic Variants into Drosophila Compound Autosome Stocks
por: Gilliland, William D., et al.
Publicado: (2016)

Molecular Phylogeography of a Human Autosomal Skin Color Locus Under Natural Selection
por: Canfield, Victor A., et al.
Publicado: (2013)

Extracellular matrix regulation of stress response genes during larval development in Caenorhabditis elegans
por: Chandler, Luke M, et al.
Publicado: (2022)

botXminer: mining biomedical literature with a new web-based application
por: Mudunuri, Uma, et al.
Publicado: (2006)

A Novel HSF4 Gene Mutation Causes Autosomal-Dominant Cataracts in a Chinese Family
por: Lv, Huibin, et al.
Publicado: (2014)

Mutation of ATF6 causes autosomal recessive achromatopsia
por: Ansar, Muhammad, et al.
Publicado: (2015)

Autosomal and X-Linked Additive Genetic Variation for Lifespan and Aging: Comparisons Within and Between the Sexes in Drosophila melanogaster
por: Griffin, Robert M., et al.
Publicado: (2016)

Transcriptomic Features of Bovine Blastocysts Derived by Somatic Cell Nuclear Transfer
por: Min, Byungkuk, et al.
Publicado: (2015)

Genome-wide identification of microRNAs involved in the somatic embryogenesis of Eucalyptus
por: Qin, Zihai, et al.
Publicado: (2021)

Knowledge and Theme Discovery across Very Large Biological Data Sets Using Distributed Queries: A Prototype Combining Unstructured and Structured Data
por: Mudunuri, Uma S., et al.
Publicado: (2013)

Long homopurine•homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region
por: Bacolla, Albino, et al.
Publicado: (2006)

FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue
por: Liggett, L. Alexander, et al.
Publicado: (2019)

Direct and Inverted Repeats Elicit Genetic Instability by Both Exploiting and Eluding DNA Double-Strand Break Repair Systems in Mycobacteria
por: Wojcik, Ewelina A., et al.
Publicado: (2012)

Trajectory of Unawareness of Memory Decline in Individuals With Autosomal Dominant Alzheimer Disease
por: Vannini, Patrizia, et al.
Publicado: (2020)

Caenorhabditis elegans SWI/SNF Subunits Control Sequential Developmental Stages in the Somatic Gonad
por: Large, Edward E., et al.
Publicado: (2014)

Differentially and Co-expressed Genes in Embryo, Germ-Line and Somatic Tissues of Tribolium castaneum
por: Khan, Sher Afzal, et al.
Publicado: (2019)

Germline Proliferation Is Regulated by Somatic Endocytic Genes via JNK and BMP Signaling in Drosophila
por: Tang, Yaning, et al.
Publicado: (2017)

A Screen for F1 Hybrid Male Rescue Reveals No Major-Effect Hybrid Lethality Loci in the Drosophila melanogaster Autosomal Genome
por: Cuykendall, Tawny N., et al.
Publicado: (2014)

Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting in Caenorhabditis elegans Somatic Tissues
por: Blazie, Stephen M., et al.
Publicado: (2017)

SKN-1 Is a Negative Regulator of DAF-16 and Somatic Stress Resistance in Caenorhabditis elegans
por: Deng, Jianhui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r62loro96hjoda909508m61avr