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WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools

Motivation: As the number of studies looking at differences between DNA methylation increases, there is a growing demand to develop and benchmark statistical methods to analyse these data. To date no objective approach for the comparison of these methods has been developed and as such it remains dif...

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Detalles Bibliográficos
Autores principales: Rackham, Owen J. L., Dellaportas, Petros, Petretto, Enrico, Bottolo, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495289/
https://www.ncbi.nlm.nih.gov/pubmed/25777524
http://dx.doi.org/10.1093/bioinformatics/btv114