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Mathematical Modelling of Metabolic Regulation in Aging

The underlying cellular mechanisms that characterize aging are complex and multifaceted. However, it is emerging that aging could be regulated by two distinct metabolic hubs. These hubs are the pathway defined by the mammalian target of rapamycin (mTOR) and that defined by the NAD+-dependent deacety...

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Detalles Bibliográficos
Autores principales: Mc Auley, Mark T., Mooney, Kathleen M., Angell, Peter J., Wilkinson, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495371/
https://www.ncbi.nlm.nih.gov/pubmed/25923415
http://dx.doi.org/10.3390/metabo5020232