Cargando…

Intestinal apical polarity mediates regulation of TORC1 by glucosylceramide in C. elegans

TORC1 (target of rapamycin complex 1) plays a central role in regulating growth, development, and behavior in response to nutrient cues. We previously showed that leucine-derived monomethyl branched-chain fatty acids (mmBCFAs) and derived glucosylceramide promote intestinal TORC1 activity for post-e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Huanhu, Sewell, Aileen K., Han, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495394/
https://www.ncbi.nlm.nih.gov/pubmed/26109047
http://dx.doi.org/10.1101/gad.263483.115