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TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT

Urinary bladder cancer (UBC) patients at muscle invasive stage have poor clinical outcome, due to high propensity for metastasis. Cancer-associated fibroblasts (CAFs), one of the principal constituents of the tumor stroma, play an important role in tumor development. However, it is unclear whether C...

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Detalles Bibliográficos
Autores principales: Zhuang, Junlong, Lu, Qun, Shen, Bing, Huang, Xiaojing, Shen, Lan, Zheng, Xi, Huang, Ruimin, Yan, Jun, Guo, Hongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495469/
https://www.ncbi.nlm.nih.gov/pubmed/26152796
http://dx.doi.org/10.1038/srep11924