Angiotensin type 1a receptor deficiency decreases amyloid β-protein generation and ameliorates brain amyloid pathology

Alzheimer’s disease is characterized by neuronal loss and cerebral accumulation of amyloid-β protein (Aβ) and lowering the generation of Aβ is a pivotal approach in the strategy of Alzheimer’s disease treatment. Midlife hypertension is a major risk factor for the future onset of sporadic Alzheimer’s...

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Detalles Bibliográficos
Autores principales: Liu, Junjun, Liu, Shuyu, Matsumoto, Yukino, Murakami, Saki, Sugakawa, Yusuke, Kami, Ayako, Tanabe, Chiaki, Maeda, Tomoji, Michikawa, Makoto, Komano, Hiroto, Zou, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495558/
https://www.ncbi.nlm.nih.gov/pubmed/26154270
http://dx.doi.org/10.1038/srep12059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495558/
https://www.ncbi.nlm.nih.gov/pubmed/26154270
http://dx.doi.org/10.1038/srep12059

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