Cargando…
Angiotensin type 1a receptor deficiency decreases amyloid β-protein generation and ameliorates brain amyloid pathology
Alzheimer’s disease is characterized by neuronal loss and cerebral accumulation of amyloid-β protein (Aβ) and lowering the generation of Aβ is a pivotal approach in the strategy of Alzheimer’s disease treatment. Midlife hypertension is a major risk factor for the future onset of sporadic Alzheimer’s...
Autores principales: | Liu, Junjun, Liu, Shuyu, Matsumoto, Yukino, Murakami, Saki, Sugakawa, Yusuke, Kami, Ayako, Tanabe, Chiaki, Maeda, Tomoji, Michikawa, Makoto, Komano, Hiroto, Zou, Kun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495558/ https://www.ncbi.nlm.nih.gov/pubmed/26154270 http://dx.doi.org/10.1038/srep12059 |
Ejemplares similares
-
New amyloid plaques or a game of hide-and-seek?
por: Zou, Kun, et al.
Publicado: (2008) -
ATP increases the migration of microglia across the brain endothelial cell monolayer
por: Maeda, Tomoji, et al.
Publicado: (2016) -
Defensive effect of microRNA-200b/c against amyloid-beta peptide-induced toxicity in Alzheimer's disease models
por: Higaki, Sayuri, et al.
Publicado: (2018) -
Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts
por: Zou, Kun, et al.
Publicado: (2022) -
Amyloid β-Sheet Mimics that Antagonize Amyloid Aggregation and Reduce Amyloid Toxicity
por: Cheng, Pin-Nan, et al.
Publicado: (2012)