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Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation

Deregulation of inflammasome activation was recently identified to be involved in the pathogenesis of various inflammatory diseases. Although macrolide antibiotics display well described immunomodulatory properties, presumably involved in their clinical effects, their impact on inflammasome activati...

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Detalles Bibliográficos
Autores principales: Gualdoni, Guido A., Lingscheid, Tilman, Schmetterer, Klaus G., Hennig, Annika, Steinberger, Peter, Zlabinger, Gerhard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495566/
https://www.ncbi.nlm.nih.gov/pubmed/26152605
http://dx.doi.org/10.1038/srep12016