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Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation
Deregulation of inflammasome activation was recently identified to be involved in the pathogenesis of various inflammatory diseases. Although macrolide antibiotics display well described immunomodulatory properties, presumably involved in their clinical effects, their impact on inflammasome activati...
Autores principales: | Gualdoni, Guido A., Lingscheid, Tilman, Schmetterer, Klaus G., Hennig, Annika, Steinberger, Peter, Zlabinger, Gerhard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495566/ https://www.ncbi.nlm.nih.gov/pubmed/26152605 http://dx.doi.org/10.1038/srep12016 |
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