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High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7

BACKGROUND: Carbonic anhydrase IX (CA9) is a transmembrane glycoprotein related to hypoxia. Increased CA9 expression has been associated with decreased survival and cancer progression and has been targeted as a potential therapy for several cancers, including esophageal cancer. The reported percenta...

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Detalles Bibliográficos
Autores principales: Huber, Aaron R., Tan, Dongfeng, Sun, Jun, Dean, David, Wu, Tongtong, Zhou, Zhongren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495619/
https://www.ncbi.nlm.nih.gov/pubmed/26156831
http://dx.doi.org/10.1186/s12876-015-0310-6