Structural basis of blocking integrin activation and deactivation for anti-inflammation

Integrins mediate leukocyte accumulation to the sites of inflammation, thereby enhancing their potential as an important therapeutic target for inflammatory disorders. Integrin activation triggered by inflammatory mediators or signaling pathway is a key step to initiate leukocyte migration to inflam...

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Detalles Bibliográficos
Autores principales: Park, Eun Jeong, Yuki, Yoshikazu, Kiyono, Hiroshi, Shimaoka, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495637/
https://www.ncbi.nlm.nih.gov/pubmed/26152212
http://dx.doi.org/10.1186/s12929-015-0159-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495637/
https://www.ncbi.nlm.nih.gov/pubmed/26152212
http://dx.doi.org/10.1186/s12929-015-0159-6

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