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Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis

BACKGROUND: Recent clinical studies show that tyrosine kinase inhibitors slow the rate of lung function decline and decrease the number of acute exacerbations in patients with Idiopathic Pulmonary Fibrosis (IPF). However, in the murine bleomycin model of fibrosis, not all tyrosine kinase signaling i...

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Detalles Bibliográficos
Autores principales: MacKenzie, BreAnne, Korfei, Martina, Henneke, Ingrid, Sibinska, Zaneta, Tian, Xia, Hezel, Stefanie, Dilai, Salma, Wasnick, Roxana, Schneider, Beate, Wilhelm, Jochen, El Agha, Elie, Klepetko, Walter, Seeger, Werner, Schermuly, Ralph, Günther, Andreas, Bellusci, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495640/
https://www.ncbi.nlm.nih.gov/pubmed/26138239
http://dx.doi.org/10.1186/s12931-015-0242-2