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Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy

PURPOSE: Radiofrequency thermal ablation (RFA) of hepatic and renal tumors can be accompanied by non-desired tumorigenesis in residual, untreated tumor. Here, we studied the use of micelle-encapsulated siRNA to suppress IL-6-mediated local and systemic secondary effects of RFA. METHODS: We compared...

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Detalles Bibliográficos
Autores principales: Ahmed, Muneeb, Kumar, Gaurav, Navarro, Gemma, Wang, Yuanguo, Gourevitch, Svetlana, Moussa, Marwan H., Rozenblum, Nir, Levchenko, Tatyana, Galun, Eithan, Torchilin, Vladimir P., Goldberg, S. Nahum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495977/
https://www.ncbi.nlm.nih.gov/pubmed/26154425
http://dx.doi.org/10.1371/journal.pone.0128910