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MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease

Recent studies have found that extracellular vesicles (EVs) play an important role in normal and disease processes. In the present study, we isolated and characterized EVs from the brains of rhesus macaques, both with and without simian immunodeficiency virus (SIV) induced central nervous system (CN...

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Detalles Bibliográficos
Autores principales: Yelamanchili, Sowmya V., Lamberty, Benjamin G., Rennard, Deborah A., Morsey, Brenda M., Hochfelder, Colleen G., Meays, Brittney M., Levy, Efrat, Fox, Howard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496044/
https://www.ncbi.nlm.nih.gov/pubmed/26154133
http://dx.doi.org/10.1371/journal.ppat.1005032